The exceptional stem cell system of Macrostomum lignano: Screening for gene expression and studying cell proliferation by hydroxyurea treatment and irradiation
نویسندگان
چکیده
منابع مشابه
The Flatworm Macrostomum lignano Is a Powerful Model Organism for Ion Channel and Stem Cell Research
Bioelectrical signals generated by ion channels play crucial roles in many cellular processes in both excitable and nonexcitable cells. Some ion channels are directly implemented in chemical signaling pathways, the others are involved in regulation of cytoplasmic or vesicular ion concentrations, pH, cell volume, and membrane potentials. Together with ion transporters and gap junction complexes,...
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PIWI proteins and piRNA pathways are essential for transposon silencing and some aspects of gene regulation during animal germline development. In contrast to most animal species, some flatworms also express PIWIs and piRNAs in somatic stem cells, where they are required for tissue renewal and regeneration. Here, we have identified and characterized piRNAs and PIWI proteins in the emerging mode...
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1 European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Antonius Deusinglaan 1, 9713AV, Groningen, The Netherlands. 2 Hubrecht Institute-KNAW and University Medical Centre Utrecht, Uppsalalaan 8, 3584CT, Utrecht, The Netherlands. 3 Institute of Cytology and Genetics, Prospekt Lavrentyeva 10, 630090 Novosibirsk, Russia. 4 Institute o...
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Background: Cancer is a significant public health problem. Some studies indicated the anti-cancer effects of mesenchymal stem cells. These effects are related to stem cells or secretory mediator of them. The aim of this study was to evaluate the impact of condition medium of mesenchymal stem cells on A549 and JEG3 cancer cell lines. Methods: In an experimental study, A549 and JEG3 cell lines p...
متن کاملIncrease of Proliferation and Colonization in Mouse Spermatogonial Stem Cell by Low Intensity Ultrasound
Background Spermatogonial stem cells (SSCs) are the foundation of spermatogenesis. Sound wave especially low intensity ultrasound (LIUS) can be effective on increasing the number of cells. In this study we investigated the effect of LIUS stimulation on mouse SSCs proliferation and colonization. Methods: Isolated SSCs from neonate mice cultured in DMEM culture medium with 10% Fetal Bovine S...
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ژورنال
عنوان ژورنال: Frontiers in Zoology
سال: 2007
ISSN: 1742-9994
DOI: 10.1186/1742-9994-4-9